Table 1.
Comparison of the distribution of four ERAP1 single nucleotide polymorphisms (SNPs) between non-small cell lung cancer patients and healthy control individuals in Chinese and Poles
| SNP | Group | Chinese N (%) | Poles N (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| GG | GC | CC | GG | GC | CC | ||||
| rs26653 | Patients | 125 (29.8) | 213 (50.7) | 82 (19.5) |
χ
2 = 16.87 p = 0.0002 |
172 (54.3) | 120 (37.8) | 25 (7.9) |
χ
2 = 3.17 p = 0.2 |
| [R127P] | Controls | 76 (19.7) | 194 (50.4) | 115 (29.9) | 258 (51.0) | 219 (43.3) | 29 (5.7) | ||
| TT | TC | CC | TT | TC | CC | ||||
| rs26618 | Patients | 189 (45.0) | 195 (46.4) | 36 (8.6) |
χ
2 = 15.69 p = 0.0004 |
174 (54.9) | 121 (38.2) | 22 (6.9) |
χ
2 = 0.07 p = 0.96 |
| [I276 M] | Controls | 227 (59.0) | 134 (34.8) | 24 (6.2) | 281 (55.5) | 192 (37.9) | 33 (6.6) | ||
| CC | CT | TT | CC | CT | TT | ||||
| rs30187 | Patients | 137 (32.6) | 203 (48.3) | 80 (19.0) |
χ
2 = 11.95 p = 0.0025 |
138 (43.6) | 137 (43.2) | 42 (13.2) |
χ
2 = 1.07 p = 0.58 |
| [K528R] | Controls | 87 (22.6) | 198 (51.4) | 100 (26.0) | 228 (45.0) | 223 (44.1) | 55 (10.9) | ||
| CC | CG | GG | CC | CG | GG | ||||
| rs27044 | Patients | 160 (38.1) | 189 (45.0) | 71 (16.9) |
χ
2 = 17.47 p = 0.00016 |
170 (53.6) | 118 (37.2) | 29 (9.2) |
χ
2 = 1.13 p = 0.57 |
| [Q730E] | Controls | 95 (24.7) | 201 (52.2) | 89 (23.1) | 275 (54.3) | 195 (38.6) | 36 (7.1) | ||
Chinese: patients N = 420; controls N = 385. Poles: patients N = 317; controls N = 506