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. 2016 Oct 14;20(1):4–9. doi: 10.1007/s11102-016-0754-x

Table 3.

Duration of symptoms until diagnosis in acromegaly as reported in population studies

Reference Duration of symptoms until diagnosis (years)
Median (range)
Total population Males Females
Fernandez et al. [3] Median 4.5 (range 1.5–15.0) Median 3.0 (range 1.5–15.0) Median 6.0 (range 3.0–15.0)
Daly et al. [4] Median 5 (range 1–25) Median 5.5 (range 1–25) Median 3 (range 1.6–5)
Hoskuldsdottir et al. [7] “for more than 3 years in most cases” NA NA
Mestron et al. [11] “the patients’ estimates of the year in which symptoms began was around 5 years before diagnosis” NA NA

NA not available