Table 4.

Frequency of macro- and microadenomas in patients with acromegaly as reported in population studies

Reference	Adenoma size
	Macroadenoma (% of cases)		Microadenoma (% of cases)
	Males	Females	Males	Females
Fernandez et al. [3]	85.7		14.3
Daly et al. [4]	88.9a		0
	100	66.7a	0	0a
Tjornstrand et al. [5]	78	77	22	23
Agustsson et al. [6]	62.5	71.4	28.1	23.8
Raappana et al. [8]	78		22
Dal et al. [9]	69		31
Bex et al. [10]	79a		16a
Mestron et al. [11]	69a		25.8a
Gruppetta et al. [12]	73.1		26.9
	68.2	76.7	31.8	23.3
Kwon et al. [14]	82.9		17.1

^aPercentages do not add up to 100 due to cases with unknown tumor size