Table 2.
Laboratory and echocardiographic data in warfarin and dabigatran groups
| Warfarin (n = 65) | Dabigatran (n = 65) | p value | |
|---|---|---|---|
| Laboratory data | |||
| PT-INR | 2.2 ± 0.5 | 1.2 ± 0.3 | <0.001 |
| APTT (s) | 43 ± 8 | 44 ± 12 | 0.401 |
| Hematocrit (%) | 41 ± 4 | 41 ± 5 | 0.474 |
| Ccr (mL/min) | 67 ± 24 | 71 ± 21 | 0.265 |
| CRP (mg/dL) | 0.14 ± 0.51 | 0.13 ± 0.37 | 0.902 |
| BNP (pg/mL) | 144 ± 143 | 116 ± 113 | 0.226 |
| Echocardiographic data | |||
| LVDd (mm) | 47 ± 5 | 48 ± 5 | 0.418 |
| LVDs (mm) | 31 ± 6 | 30 ± 4 | 0.918 |
| LVEF (%) | 65 ± 8 | 65 ± 8 | 0.910 |
| LAD (mm) | 42 ± 8 | 41 ± 7 | 0.953 |
| LAA flow (cm/s) | 39 ± 20 | 42 ± 19 | 0.394 |
| Left atrial thrombus | 5 | 0 | 0.068 |
| SEC grade | |||
| Grade 0 or 1 (0/1) | 45 (32/13) | 63 (44/19) | <0.001 |
| Grade 2 or 3 (2/3) | 20 (14/6) | 2 (1/1) | |
Italics indicate metastatic SNs
PT-INR prothrombin time-international normalized ratio, APTT activated partial thromboplastin time, Ccr creatinine clearance, CRP C-reactive protein, BNP brain natriuretic peptide, LVDd left ventricular end-diastolic dimension, LVDs left ventricular end-systolic dimension, LVEF left ventricular ejection fraction, LAD left atrial dimension, LAA left atrial appendage, SEC spontaneous echo contrast