Table 3.
Factors affecting SEC grade
| SEC grade | Univariate | Multivariate | |||
|---|---|---|---|---|---|
| 0/1 (n = 108) | 2/3 (n = 22) | p value | p value | Odds ratio (95 % CI) | |
| Age (years) | 65 ± 9 | 69 ± 7 | 0.117 | – | – |
| Men | 75 (69 %) | 15 (68 %) | 0.554 | – | – |
| Previous heart failure | 19 (18 %) | 8 (36 %) | 0.045 | 0.345 | 2.599 (0.357–18.90) |
| Hypertension | 60 (56 %) | 15 (68 %) | 0.196 | – | – |
| Diabetes mellitus | 8 (7 %) | 6 (27 %) | 0.009 | 0.018 | 11.30 (1.218–576.6) |
| Cerebral infarction | 5 (5 %) | 4 (18 %) | 0.034 | 0.454 | 2.900 (0.178–47.26) |
| Paroxysmal AF | 55 (51 %) | 1 (5 %) | <0.001 | 0.020 | 0.023 (0.001–0.561) |
| CHADS2 score | 1.0 ± 0.9 | 1.9 ± 1.0 | <0.001 | 0.240 | 1.921 (0.646–5.715) |
| PT-INR | 1.6 ± 0.6 | 2.2 ± 0.6 | <0.001 | 0.058 | 6.175 (0.938–40.64) |
| APTT (sec) | 44 ± 11 | 44 ± 7 | 0.994 | – | – |
| Hematocrit (%) | 41 ± 5 | 42 ± 5 | 0.254 | – | – |
| Ccr (mL/min) | 70 ± 23 | 64 ± 21 | 0.297 | – | – |
| CRP (mg/dL) | 0.11 ± 0.30 | 0.26 ± 0.88 | 0.177 | – | – |
| BNP (pg/mL) | 111 ± 109 | 223 ± 175 | <0.001 | 0.010 | 1.008 (1.002–1.015) |
| LVDd (mm) | 47 ± 5 | 48 ± 5 | 0.757 | – | – |
| LVDs (mm) | 30 ± 5 | 31 ± 5 | 0.388 | – | – |
| LVEF (%) | 65 ± 8 | 63 ± 10 | 0.218 | – | – |
| LAD (mm) | 41 ± 7 | 44 ± 11 | 0.047 | 0.647 | 1.018 (0.940–1.103) |
| Dabigatran usage | 63 (58 %) | 2 (9 %) | <0.001 | 0.047 | 0.019 (0.001–0.963) |
Italics indicate metastatic SNs
SEC spontaneous echo contrast, AF atrial fibrillation, PT-INR prothrombin time-international normalized ratio, APTT activated partial thromboplastin time, Ccr creatinine clearance, CRP C-reactive protein, BNP brain natriuretic peptide, LVDd left ventricular end-diastolic dimension, LVDs left ventricular end-systolic dimension, LVEF left ventricular ejection fraction, LAD left atrial dimension