. 2016 Jul 13;222(2):669–706. doi: 10.1007/s00429-016-1250-9

Table 1.

Characteristics of IT (intratelencephalic) and PT (pyramidal tract) corticostriatal neurons

Corticostriatal neurons	PT	IT
Classified by	Pyramidal tract axon	Intratelencephalic axon
Laminar location^a	Layer 5, densest in 5B	Layers 2–6, densest in 5A and 3
Neural morphology^b,c,d	Large pyramidal; profuse dendritic arborisation in layer 1	Medium sized pyramidal; sparser dendritic arborisation in layer 1
Laterality of axonal arborisation	Strictly unilateral	Frequently bilateral
Extrastriatal collateral^b,c,e,f	Subthalamic nucleus, thalamus, brainstem, spinal cord	Cortex, claustrum
Striatal collateral	Thin collateral off main subcortical axonal trunk	Main subcortical axon
Striatal arborisation (l.m.)^f	Scarce and widespread; longer terminals	Scarce and widespread; shorter terminals
Striatal terminals (e.m.)^a,g,h	Large (50 % wider diameter)	Small
Preferential contact with striatal SPN^g,h	dSPN 36 %	dSPN 54 %
Preferential contact with striatal SPN^g,h	iSPN 64 %	iSPN 46 %
Short-term synaptic action upon dSPNⁱ	Depressive	Facilitatory
Short-term synaptic action upon iSPNⁱ	Facilitatory	Depressive

l.m. light microscope, e.m. electron microscope

^aReiner et al. (2003), ^b Wilson (1987), ^c Cowan and Wilson (1994), ^d Morishima and Kawaguchi (2006), ^e Kita and Kita (2012), ^f Parent and Parent (2006), ^g Reiner et al. (2010), ^h Deng et al. (2015), ⁱ Morita (2014)