Table 1.
Participant characteristics of the discovery and replication studies
| Discovery Bakker et al. 2014 |
Replication 1 Vosselman et al. 2015 |
Replication 2 Vosselman et al. 2015 |
Replication 3 Vosselman et al. 2012, 2013 |
|
|---|---|---|---|---|
| Age (years) | 24.1 (21.7–26.6) | 25.7 (22.0–32.0) | 22.8 (19.0–24.5) | 22.8 (21.0–24.0) |
| N (% males) | 22 (100%) | 11 (100%) | 10 (100%) | 16 (100%) |
| Body mass index (kg/m2) | 22.1 (20.5–23.4) | 21.2 (19.5–22.5) | 22.1 (21.3–23.4) | 22.1 (20.7–23.3) |
| Ethnicity (n of participants) | ||||
| White Caucasian (%) | 10 (46%) | 11 (100%) | 10 (100%) | 16 (100%) |
| South Asian (%) | 12 (54%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Brown adipose tissue volume (mL) | 230 (158–299) | 288 (164–480) | 802 (551–1010)* | 480 (167–766)* |
| Brown adipose tissue activity (SUVmean, g/mL) | 4.17 (4.01–4.36) | 2.12 (1.79–2.34) | 2.52 (2.33–2.90) | 2.35 (2.09–2.64) |
Values represent number of participants (%) or median (interquartile range). *p < 0.05 vs Discovery study