Table 2.
Genotypes’ distributions of BTLA gene polymorphisms among CLL patients and the controls
| SNP | Genotype | Cases | Controls | OR | 95% CI | Cases vs. controls | |||
|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | ||||||
| rs2705511 | AA | 142 | 44.2 | 263 | 56.0 | 1 | – | – |
χ
2df=1 = 11.83 p = 0.0006 |
| AC | 159 | 49.5 | 175 | 37.2 | 1.68 | 1.25 | 2.26 | ||
| CC | 20 | 6.2 | 32 | 6.8 | 1.17 | 0.65 | 2.10 | ||
| rs1982809 | AA | 156 | 48.6 | 279 | 59.4 | 1 | – | – |
χ
2df=1 = 8.93 p = 0.0028 |
| AG | 143 | 44.5 | 163 | 34.7 | 1.57 | 1.16 | 2.11 | ||
| GG | 22 | 6.9 | 28 | 6.0 | 1.41 | 0.78 | 2.53 | ||
| rs9288952 | AA | 289 | 90.0 | 415 | 88.3 | 1 | – | – |
χ
2df=1 = 0.58 p = 0.4442 |
| AG | 31 | 9.7 | 53 | 11.3 | 0.85 | 0.53 | 1.35 | ||
| GG | 1 | 0.3 | 2 | 0.4 | 0.86 | 0.11 | 6.56 | ||
| rs9288953 | CC | 101 | 31.5 | 185 | 39.4 | 1 | – | – |
χ
2df=1 = 9.69 p = 0.0018 |
| CT | 150 | 46.7 | 220 | 46.8 | 1.25 | 0.91 | 1.72 | ||
| TT | 70 | 21.8 | 65 | 13.8 | 1.97 | 1.30 | 2.98 | ||
| rs2705535 | CC | 315 | 98.1 | 456 | 97.0 | 1 | – | – |
χ
2df=1 = 0.95 p = 0.3290 |
| CT | 6 | 1.9 | 14 | 3.0 | 0.65 | 0.25 | 1.65 | ||
| TT | 0 | 0 | 0 | 0 | 1.45 | 0.03 | 73.12 | ||
| rs1844089 | GG | 270 | 84.1 | 389 | 82.8 | 1 | – | – |
χ
2df=1 = 0.27 p = 0.6015 |
| GA | 50 | 15.6 | 79 | 16.8 | 0.91 | 0.62 | 1.34 | ||
| AA | 1 | 0.3 | 2 | 0.4 | 0.86 | 0.11 | 6.58 | ||
| rs2705565 | CC | 292 | 91.0 | 421 | 89.6 | 1 | – | – |
χ
2df=1 = 0.53 p = 0.4662 |
| CT | 29 | 9.0 | 48 | 10.2 | 0.88 | 0.54 | 1.42 | ||
| TT | 0 | 0.0 | 1 | 0.2 | 0.48 | 0.02 | 11.83 | ||
| rs2633580 | CC | 274 | 85.4 | 393 | 83.6 | 1 | – | – |
χ
2df=1 = 0.56 p = 0.4544 |
| CG | 46 | 14.3 | 74 | 15.7 | 0.89 | 0.60 | 1.33 | ||
| GG | 1 | 0.3 | 3 | 0.6 | 0.61 | 0.09 | 4.19 | ||
* Distribution estimated numerically