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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: JAMA Surg. 2017 Feb 1;152(2):157–166. doi: 10.1001/jamasurg.2016.4065

Table 4.

Individual PPCs and Clinical Outcomes

Individual PPCs All Patients
(n = 1202)
Hospital ICU 7-d Mortality
(n = 9)
Patients, No. (%)
(n = 1179)
LOS, Median
(IQR), d
Patients, No. (%)
(n = 270)
LOS, Median
(IQR), d
Pneumonia
    Yes 22 (1.8) 22 (100.0) 12.0 (7.0–21.0)a 10 (45.5)b 6.1 (3.0–9.0)c 2 (9.1)b
    No 1180 (98.2) 1157 (98.1) 4.0 (2.0–7.0) 260 (22.0) 2.0 (1.0–4.0) 7 (0.6)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 8.00 (2.44–15.68) 2.06 (1.29–3.30) 4.0 (0.95–7.11) 15.3 (3.4–69.4)
Pneumothorax
    Yes 4 (0.3) 4 (100.0) 6.7 (5.0–10.7) 2 (50.0) 1.3 (0.5–2.0) 0 (0)
    No 1188 (99.7) 1175 (98.1) 4.0 (2.1–7.0) 268 (22.4) 2.0 (1.0–4.0) 9 (0.8)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 1.0 (1.0–8.81) 2.24 (0.83–5.99) −1.50d NDd
Atelectasis
    Yes 206 (17.1) 206 (100.0)b 7.4 (5.0–13.0)a 87 (42.2)a 3.0 (1.8–6.0)a 9 (4.4)a
    No 996 (82.9) 973 (97.7) 4.0 (2.0–6.0) 183 (18.4) 2.0 (1.0–3.0) 0 (0.0)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 3.29 (0.56–6.81) 2.30 (1.87–2.83) 1.0 (0.87–3.25) NDd
Pleural effusion
    Yes 116 (9.7) 115 (99.1) 8.4 (5.0–16.0)a 61 (52.6)a 3.6 (2.0–7.0)a 8 (7.0)a
    No 1086 (90.3) 1064 (98.0) 4.0 (2.0 to 6.3) 209 (19.2) 2.0 (1.0–3.0) 1 (0.1)
    RR or MDiff (95% CI) NA 1.01 (0.99–1.03) 4.38 (0.52–9.17) 2.73 (2.21–3.38) 1.56 (−0.07 to 4.32) 75.3 (9.5–597.0)
Bronchospasm
    Yes 13 (1.1) 13 (100.0) 4.0 (2.8–7.0) 2 (15.4) 4.5 (2.0–7.0) 0 (0.0)
    No 1189 (98.9) 1166 (98.1) 4.0 (2.1–7.0) 268 (22.5) 2.0 (1.0–4.0) 9 (0.8)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 0 (−1.26 to 33.12) 0.68 (0.19–2.45) 0d NDd
ARDS
    Yes 2 (0.2) 2 (100.0) 17.0 (7.5–26.4) 2 (100.0) 6.9 (6.3–7.5)b 1 (50.0)b
    No 1200 (99.8) 1177 (98.1) 4.0 (2.1–7.0) 268 (22.3) 2.0 (1.0–4.0) 8 (0.7)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 3.50d 4.48 (4.03–4.98) 4.25d 74.8 (15.9–351.6)
Respiratory dysfunction requiring prolonged (>1 d) postoperative O2 by NC
    Yes 235 (19.6) 235 (100.0)b 6.0 (4.0–9.7)a 72 (30.6)a 3.0 (2.0–6.0)a 1 (0.4)
    No 967 (80.4) 944 (97.6) 4.0 (2.0–6.0) 198 (20.5) 2.0 (1.0–3.0) 8 (0.8)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 2.0 (2.0–4.38) 1.5 (1.19–1.88) 1.0 (0.48–2.89) 0.51 (0.06–4.08)
Respiratory dysfunction requiring prolonged (>1 d) postoperative O2 by face mask
    Yes 12 (1.0) 12 (100.0) 14.5 (5.6–23.0)a 10 (83.3)a 6.6 (3.0–11.0)a 0 (0)
    No 1190 (99.0) 1167 (98.1) 4.0 (2.0–7.0) 260 (21.8) 2.0 (1.0–4.0) 9 (0.8)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 7.0 (1.97–18.76) 3.81 (2.90–5.02) 4.15 (0.95–9.38) NDd
Postoperative-noninvasive ventilation
    Yes 46 (3.8) 44 (95.7) 6.0 (3.0–9.5)b 16 (34.8)b 6.1 (2.5–7.5)a 2 (4.3)b
    No 1156 (96.2) 1135 (98.2) 4.0 (2.0–7.0) 254 (22.0) 2.0 (1.0–3.8) 7 (0.6)
    RR or MDiff (95% CI) NA 0.97 (0.92–1.04) 2.0 (−1.52 to 5.74) 1.58 (1.05–2.39) 4.0 (1.18–5.82) 7.2 (1.5–33.5)
Reintubation + postoperative mechanical ventilation
    Yes 21 (1.7) 21 (100.0) 21.0 (9.0–26.0)a 19 (90.5)a 7.0 (5.0–11.6)a 3 (14.3)a
    No 1181 (98.3) 1158 (98.1) 4.0 (2.0–7.0) 251 (21.3) 2.0 (1.0–3.5) 6 (0.5)
    RR or MDiff (95% CI) NA 1.02 (1.01–1.03) 17.0 (5.14–22.40) 4.26 (3.57–5.08) 5.0 (4.09–9.37) 28.0 (7.5–104.6)

Abbreviations: ARDS, acute respiratory distress syndrome; ICU, intensive care unit; IQR, interquartile range; LOS, length of stay; MDiff, median difference; O2, oxygen; NA, not applicable; NC, nasal cannula; ND, not defined; O2, oxygen; PPC, postoperative pulmonary complication; RR, relative risk.

a

P < .001 yes vs no for individual PPCs.

b

P < .05

c

P < .01

d

RR or MDiff (95% CI) calculated as not defined or not calculated.