Management algorithm for patients with acute UEDVT diagnosed on Doppler ultrasound. DOAC, direct oral anticoagulant; LMWH, low-molecular-weight heparin; PICC, peripherally inserted central catheter; UEDVT, upper extremity deep vein thrombosis. *Indications for removal are catheter malfunction, improper positioning, infection, progressive symptoms, and no longer necessary catheters.