Figure 5.

Predictive coding and active inference. (A) Waking perception is modeled as a series of forward connections between the Lateral Geniculate Body and the Visual Cortex, facilitated by the presence of Serotonin (5-HT), thus allowing retinal input to ascend. (B) The absence of 5-HT in sleep dampens the postsynaptic sensitivity of superficial pyramidal neuron groups, progressively reducing the capacity for retinal information to ascend through the Visual Cortex and become processed into vision, which now forms though feedback connections. Image reproduced from Hobson and Friston (2012).