Table 2.
Parameters | Description | Default value assumed or range of values explored |
---|---|---|
n | Number of individuals in the simulation | 10 000 |
μb | Mean baseline TL | 7000 bp |
σb | Standard deviation of baseline TL | 700 bp |
μa | Mean telomere attrition per year | 30 bp year−1 |
σa | Standard deviation of annual telomere attrition | 0, 50 and 100 bp |
r | Autocorrelation between telomere attrition in successive years | 0, 0.5 and 1 |
CV | Coefficient of variation of measurement error | 2, 4 and 8% |
y max | Maximum follow‐up period | 15 years |