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. 2017 Jan 26;16(2):210–218. doi: 10.1111/acel.12562

Figure 2.

Figure 2

A comparison of a normal ‘healthy’ articular joint with that of a joint with OA. We also highlight the characteristics of the senescent phenotype that could potentially play a role in specific alterations seen in OA (seen in blue). (A) A diagram of a normal healthy joint. (B) A diagram of an OA‐affected joint, highlighting common changes, for example, cartilage degradation; synovial hypertrophy often accompanied by inflammation (synovitis); formation of peri‐articular osteophytes; osteosclerosis of subchondral bone.