Table 5.
Factors influencing QoL in patients with active acromegaly (cross-sectional).
| Reference | General factors |
Disease-specific factors |
|||||
|---|---|---|---|---|---|---|---|
| Depression | Age | Female gender | IGF1 | GH | Disease duration | Biochemical control | |
| Hua et al. (9) | 0 | ||||||
| Leon-Carrion et al. (43) | −− | ++ | ++ | ||||
| Matta et al. (47) | + | ||||||
| Sardella et al. (58) | 0 | − | |||||
| Vandeva et al. (63) | −− | −− | 0 | ||||
| Varewijck et al. (64) | − | ||||||
++positive correlation with QoL, +positive correlation with a subscale of QoL only, −−negative correlation with QoL, −negative correlation with a subscale of QoL only, 0 no significant correlation with QoL.