Table 6.

Factors influencing QoL in patients with acromegaly in remission (cross-sectional).

Reference	General factors			Disease-specific factors
	Age	Female gender	Depression	Biochemical control	IGF1	Hypopituitarism	GH	Radiotherapy	Disease duration	Remission duration	Followup duration	Change in IGF1
Biermasz et al. (23)	−	0	−−		0	0	+	−	0	−	−
Biermasz et al. (24)	−−						+	−	−−
Bonapart et al. (25)					0		−−
Hua et al. (9)				0
Matta et al. (47)				+
Neggers et al. (50)							0					0
Sardella et al. (58)				−					0
van der Klaauw et al. (62)	+/−	−−				0		−		0
Vandeva et al. (63)	−−									0
Varewijck et al. (64)					−
Wassenaar et al. (65)	+/−				0	0	0a	−	0	0

++positive correlation with QoL, +positive correlation with a subscale of QoL only, −− negative correlation with QoL, −negative correlation with a subscale of QoL only, 0 no significant correlation with QoL.

^aNadir GH.