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. Author manuscript; available in PMC: 2018 Mar 2.
Published in final edited form as: Curr Protoc Chem Biol. 2017 Mar 2;9(1):1–10. doi: 10.1002/cpch.16

Figure 1. The BAF complex hydrolyzes ATP and alters chromatin structure.

Figure 1

Recent studies have revealed that SWI/SNF complexes are capable of altering chromatin accessibility, nucleosome positioning, and Polycomb activity. It is presently unknown whether these chromatin-remodeling activities rely strongly on the ATPase activity of the complexes or whether catalytic mutations may alter the ability of SWI/SNF complexes to regulate chromatin structure with unique downstream effects.