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Effects of VCD and parabens on the mRNA expression of steroidogenic enzymes in rats ovaries. The expressions of Star, Cyp11a1, Cyp19a1 and Hsd3b1 gene were measured by real-time PCR and normalized by Rn18s. (A) Star; (B) Cyp11a1; (C) Cyp19a1; (D) Hsd3b1. a p < 0.05 vs. VE, b p < 0.05 vs. paraben, c p < 0.05 vs. VCD. Data are presented as the mean ± SD. VE 20% Et-OH, VCD 40 mg/kg/day, MP, PP, BP; 100 mg/kg/day.
