Figure 3.
Comparison of PR-10 food and plant allergens with known structures. (A) Overlay of the lowest energy structure of Mal d 1.0101 (green, PDB accession code 5MMU) with the structures of the major birch pollen allergen Bet v 1.0101 (blue, 4A88), the carrot allergen Dau c 1.0103 (orange, 2WQL), the celery allergen Api g 1.0101 (gray, 2BK0), the soybean allergen Gly m 4.0101 (yellow, 2K7H), the strawberry allergen Fra a 1E (red, 2LPX), and the cherry allergen Pru av 1.0101 (purple, 1E09). (B) Multiple sequence alignment of these allergens obtained with Clustal Omega.53 Amino acids are marked with asterisks (identical), colons (conserved), and dots (semiconserved). Secondary structure elements as present in Mal d 1.0101 are indicated.