Table 1. Main physicochemical characterization for uncoated and CS-coated NPs.

	Medium	MIL-100(Fe)	CS_MIL-100(Fe)
BET surface area (m2g−1)		1570	1590*
Size (nm)	Water	135 ± 20	204 ± 32
	PBS	155 ± 61	182 ± 50
	lis-SIF	147 ± 54	175 ± 30
	lis-SIF-panc	168 ± 45	908 ± 36
	lis-SIF-muc	254 ± 40	478 ± 85
	DMEM	146 ± 37	273 ± 21
	HBSS	163 ± 30	165 ± 5
ζ-potential (mV)	Water	−18 ± 5	+38 ± 5
	PBS	−31 ± 0	−28 ± 0
	lis-SIF	−51 ± 1	−5 ± 3
	lis-SIF-panc	−7 ± 2	−6 ± 3
	lis-SIF-muc	−6 ± 1	−13 ± 9
	DMEM	−8 ± 2	−24 ± 0
	HBSS	−18 ± 1	+18 ± 2

For all media, both size and ζ-potential are measured in 5 min-aged suspensions to ensure comparable situations.

^*BET surface area weight corrected by considering the presence of CS in the sample.