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. 2017 Mar 3;7:43770. doi: 10.1038/srep43770

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The predicted topologies of odorant, gustatory, and ionotropic receptors, showing distribution of non-synonymous substitutions (β > α > 0) on conserved residues (see methods, Figure S4) between D. nigrosparsa and the 12 Drosophila species (blue circles) and conserved cysteines (orange circles) along protein domains. Seven trans-membrane domains were inferred for ORs and GRs, three for IRs.