Table 2. Enriched gene networks recruited by 90/5 action potential patterned stimulation for 5 hr.

Network	Score	Top Disease and Function	Focus Molecules
1	39	Cell Morphology, Connective Tissue Development and Function, Tissue Morphology	ABCC5, ABCF1, ATM/ATR, CDKAL1, CTU1, DDX52, DPH2, FAM120B, GPANK1, GULP1, HLCS, KIAA1161, MMS19, MON2, MSL2, MXD3, MYO18A, NCAPD3, NCAPH2, NKAP, ORAOV1, PHLPP1, PRIM2, RBM39, SLC12A2, SLC30A1, SLC38A2, SLC4A7, SLC7A1, SMC2, SMC3, SNX27, SRC
2	38	Neurological Disease, Small Molecule Biochemistry, Developmental Disorder	ACAD10, APP, ATCAY, CHCHD6, DPY19L3, FRMD8, GSPT2, HBS1L, IMP4, ISOC2, KCTD18, LETM2, LHFPL2, MAB21L2, NARF, ORMDL1, PATL1, PHACTR4, PLEKHO2, PUS7L, RAB39A, RCBTB1, RNF24, RP9, Rbfox3, SLC25A38, SLC41A3, TBC1D25, TCP11L2, UGGT2, ULK4, VAT1L, ZC2HC1A, ZNF322, ZNF35
3	37	Post-Translational Modification, Cell Morphology, Cellular Assembly and Organization	AFAP1, ATE1, Ank2, CEP170, DUB, FTO, HERC2, KCNC4, KIF3A, KIF3B, KIF3C, MED20, NPR2, PAN2, PCYT1A, Par6, Pkc(s), RNF168, SLC18A3, SLC6A9, TRIM46, USP1, USP10, USP12, USP28, USP29, USP30, USP32, USP38, USP40, USP42, USP54, WDR20, WDR62, ZRANB1
4	37	Cancer, Gastrointestinal Disease, Organismal Injury and Abnormalities	ABR, ADIPOR2, AGL, APPL1, CENPC, DARS2, DPYSL5, EIF5B, ERBB2IP, GAPVD1, INSM1, KCNA5, KCNS3, KCTD5, KIF26B, MINK1, MPP3, NELL1, NHLRC1, NIT1, NSL1, OCRL, PKNOX1, PRKAB2, RAB11FIP5, RPAP1, Rab11, Rab5, Rac, SLTM, TPCN2, TROVE2, ZBTB3, ZFYVE9, ZNF202
5	37	Cell-To-Cell Signalling and Interaction, Cellular Movement, Cellular Development	Alpha catenin, BAG2, BSN, CCDC117, CDH2, CDH4, CDH8, CEP68, CTBP1, CTNND1, Cadherin, DEF6, ERC2, FOXJ3, HDAC11, IQSEC1, KCTD6, LTN1, MLF2, NUP85, OGT, PHF20, RBBP5, RBM22, RNF111, S1PR1, SATB1, SSPN, Spectrin, TJP1, TMEM117, TRIM26, TRMT2A, ZEB2, ZKSCAN8

Network discovery by IPA of enriched disease and function. Network score are listed for 5 top-scoring networks, encompassing processes important in cellular development, morphology, and disease.