Table 1. Yield and nucleic acid contamination characterisation of HBc particles prepared using “Conventional” or “Improved” methods.

Method	HBc code	Protein yield (mg)[1],[2]	OD260:OD280[1],[2]
Conventional	WT-HBc (C)	1.21 ± 0.3	1.02 ± 0.04
Improved	WT-HBc (I)	3.21 ± 0.21***	0.58 ± 0.01***

^[1] Values were obtained with Nanodrop from 1 litre bacteria containing media normalised to LB media.

^[2] Results are expressed an average ± SD (n = 3). ^***p = 0.00024 (<0.001) (One-way ANOVA).