Table 2. Genes selected for the three regimens. Multiple probes are selected for some genes (e.g. NFIB and H2AFZ).
Probe Set | Symbol | Description | Chromosome | pCR Status* |
---|---|---|---|---|
Anthracycline (A) regimen | ||||
218066_at | SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 5 | − |
210164_at | GZMB | Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated Serine Esterase 1) | 14 | + |
213211_s_at | TAF6L | TAF6-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65 kDa | 11 | − |
214567_s_at | XCL2 | Chemokine (C Motif) Ligand 2 | 1 | + |
Paclitaxel and anthracycline (TA) regimen | ||||
213033_s_at | NFIB | Nuclear Factor I/B | 9 | + |
219051_x_at | METRN | Meteorin, Glial Cell Differentiation Regulator | 16 | − |
209289_at | NFIB | Nuclear Factor I/B | 9 | + |
205225_at | ESR1 | Estrogen Receptor 1 | 6 | − |
220425_x_at | ROPN1B | Rhophilin Associated Tail Protein 1B | 3 | + |
213032_at | NFIB | Nuclear Factor I/B | 9 | + |
204822_at | TTK | TTK Protein Kinase | 6 | + |
221253_s_at | TXNDC5 | Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) | 6 | + |
208712_at | CCND1 | Cyclin D1 | 11 | − |
221872_at | RARRES1 | Retinoic Acid Receptor Responder (Tazarotene Induced) 1 | 3 | + |
203693_s_at | E2F3 | E2F transcription factor 3 | 6 | + |
204825_at | MELK | Maternal embryonic leucine zipper kinase | 9 | + |
206754_s_at | CYP2B7P | Cytochrome P450, Family 2, Subfamily B, Polypeptide 7, Pseudogene | 19 | + |
Docetaxel and anthracycline (TxA) regimen | ||||
203554_x_at | PTTG1 | pituitary tumor-transforming 1 | 5 | + |
202107_s_at | MCM2 | minichromosome maintenance complex component 2 | 3 | + |
200934_at | DEK | DEK Proto-Oncogene | 6 | + |
200853_at | H2AFZ | H2A histone family, member Z | 4 | + |
210052_s_at | TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 20 | + |
202825_at | SLC25A4 | Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide Translocator), Member 4 | 4 | − |
201930_at | MCM6 | minichromosome maintenance complex component 6 | 2 | + |
202427_s_at | BRP44 | brain protein 44 | 1 | + |
218437_s_at | LZTFL1 | Leucine Zipper Transcription Factor-Like 1 | 3 | − |
212695_at | CRY2 | Cryptochrome Circadian Clock 2 | 11 | − |
201853_s_at | CDC25B | cell division cycle 25 homolog B (S. pombe) | 20 | + |
201695_s_at | PNP | purine nucleoside phosphorylase | 14 | + |
208079_s_at | AURKA | Serine/Threonine-Protein Kinase Aurora-A | 20 | + |
204159_at | CDKN2C | Cyclin-Dependent Kinase Inhibitor 2 C | 1 | + |
202633_at | TOPBP1 | DNA Topoisomerase II-Beta-Binding Protein 1 | 3 | + |
207618_s_at | BCS1L | BC1 (Ubiquinol-Cytochrome C Reductase) Synthesis-Like | 2 | − |
212055_at | C18orf10 | Tubulin Polyglutamylase Complex Subunit 2 | 18 | + |
202951_at | STK38 | Serine/Threonine Kinase 38 | 6 | + |
201896_s_at | PSRC1 | Proline and Serine Rich Coiled-Coil 1 | 1 | + |
214435_x_at | RALA | V-Ral Simian Leukemia Viral Oncogene Homolog A (Ras Related) | 7 | + |
208920_at | SRI | Calcium Binding Protein Amplified In Mutlidrug-Resistant Cells | 7 | − |
204767_s_at | FEN1 | Flap Structure-Specific Endonuclease 1 | 11 | + |
210648_x_at | SNX3 | Sorting Nexin 3 | 6 | + |
216248_s_at | NR4A2 | Nuclear Receptor Subfamily 4 Group A Member 2 | 2 | − |
204900_x_at | SAP30 | Sin3A Associated Protein 30 kDa | 4 | + |
204822_at | TTK | Phosphotyrosine Picked Threonine-Protein Kinase | 6 | + |
214456_x_at | SAA1/2 | Serum Amyloid A1/2 | 11 | + |
203418_at | CCNA2 | Cyclin A2 | 4 | + |
207175_at | ADIPOQ | Adiponectin, C1Q And Collagen Domain Containing | 3 | + |
221599_at | C11orf67 | Adipogenesis Associated, Mth938 Domain Containing | 11 | − |
*pCR status: “+”, gene expression up-regulated in pCR cases; “−”, gene expression down-regulated in pCR cases.