Table 3. PRES assignment and expected pCR for each study in the independent validation, where each independent data set being tested was left out when training the models.

Study	TA	TxA	A	pCR rate (%)
20194 original	257 (20.6%)	8 (12.5%)	4 (0)	20.1
20194 PRES	139	101	29	29.5 (25.7, 34.8)
20271 original	91 (20.9%)	—	85 (8.2%)	14.8
20271 PRES	36	49	91	29.7 (23.5, 46.6)
22093 original	—	—	50 (10%)	10
22093 PRES	—	50	—	15.6 (11.4, 19.5)
23988 original	—	61 (32.8%)	—	32.8
23988 PRES	17	44	0	45.6 (39.1, 53.1)
25055 original	290 (18.3%)	—	—	18.3
25055 PRES	0	290	0	41.1 (33.4, 49.4)
25065 original	92 (20.7%)	88 (26.1%)	—	23.3
25065 PRES	18	160	2	37.0 (29.1, 46.7)
42822 original	—	53 (37.7%)	—	37.7
42822 PRES	15	38	0	45.3 (39.1, 52.2)