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. 2017 Mar 3;7:43308. doi: 10.1038/srep43308

Figure 2. Susceptibility of BERK SCD mice to influenza.

Figure 2

(A) Weight loss after influenza challenge in BERK SCD mice (SCD) and heterozygous littermate controls (WT). (B) Survival kinetics of mice in A after influenza inoculation (WT: 1 survivor, SCD: no survivors). *p < 0.05 by Log rank test. n = 10 mice per group (C,D) Viral titers recovered from nasal and lung lavages of mice at day 6 post- inoculation. (E) Levels of IFN-γ in the BALF of mice at day 6 post–inoculation. Each data point represents an individual mouse. *p < 0.05 by log rank test. Data and error bars represent the mean and standard error for (A,C,D and E).