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. 2017 Mar 2;18:83. doi: 10.1186/s12882-016-0414-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Changes in clinical and laboratory parameters during the follow-up period. GEE analyses were used to determine mean differences over time of clinical outcomes and laboratory parameters between the two groups. Change in systolic BP (a), diastolic BP (b), hemoglobin A1C (c), serum bicarbonate (d), serum triglyceride (e), urine protein-creatinine ratio (f), 24-h urine normalized protein nitrogen appearance (g), 24-h urine sodium (h) between intervention group and control group during the follow-up period