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Ablation of Raf isoforms in chondrocytes decreases pERK1/2 and impairs hypertrophic chondrocyte apoptosis. A and B, immunostaining for pERK1/2 and cleaved caspase-9 in the tibial metaphyses of P8 (A) and E18.5 (B) mice. Data are representative of five mice per genotype.
