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. 2017 Jan 19;292(8):3366–3378. doi: 10.1074/jbc.M116.770024

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© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — Coat color correlates with Cre expression in the RPE of constitutive Dicer1^flox/floxCre^B⁺ and Dgcr8^flox/floxCre^B⁺ mice. A, images of mature RPE-specific Dicer1^flox/floxCre^B⁺ and Dgcr8^flox/floxCre^B⁺ mice reveal variations in coat color. B, quantitative RT-PCR analysis of Cre recombinase gene expression in the RPE/choroid of 8-week-old Dicer1^flox/floxCre^B⁺ and Dgcr8^flox/floxCre^B⁺ mice with different proportions of white and black fur, along with control littermates revealed that mice with more white fur also exhibited higher Cre expression in the RPE/choroid. *, p < 0.05; **, p < 0.001.