. 2017 Mar 3;12(3):e0172059. doi: 10.1371/journal.pone.0172059

Table 2. Amino acid mutations associated with the Korean H3N2 clades.

		Amino acid mutation at a given residue
Season	Clade	HA^a	NA
2011–12	I	E50K (C), P162S, I260M (E), R261Q (E)	D127N, E221K, I307M, I338F, N342D, N402D, R430S
	II	S45G (C), K62E (E), K144N (A), N145S (A), A198S (B), T212A (D)	L81P, K369T, N402D
	III	Q33R, S45N (C), T48I (C), K62E (E), K144N (A), A198S (B), T212A (D), N278K (C)	L81P, D93G, I222V, K369T, N402D
2012–14	3C.3a	Q33R, T128A (B), A138S (A), N145S (A), Q156H (B), F159S (B), V186G (B), Y219S (D), N225D (D), N278K (C)	E221D, K258E, T329N, I392T

^aHA antigenic sites (A, B, C, D, and E) are indicated in parenthesis.