Skip to main content
. 2017 Mar 3;12(3):e0172900. doi: 10.1371/journal.pone.0172900

Fig 5. The reversal effects of curcumin on peripheral immunological cells.

Fig 5

Ex vivo curcumin treatment of PBMCs from patients with NAFLD resulted in decreases in (A) linoleic acid-induced reactive oxygen species generation (n = 9, *p = 0.011) and (B) leptin-induced TNF-α production (n = 9, *p = 0.016) by monocytes. (C) Ex vivo curcumin treatment of PBMCs from patients with NAFLD resulted in decreased IFN-γ production in CD4+ cells (n = 9, *p = 0.048). Lines connect the “Linoleic acid” and “Linoleic acid+Curcumin” stimulation indexes or the “Leptin” and "Leptin+Curcumin" fold of increase indexes for each patient. A Wilcoxon matched-pairs signed rank test was performed.