Table 3. Rates of composite severe neonatal morbidity/mortality and prognostic performance of the INTERGROWTH-21^st Project standard and the Canadian reference among all live births and among low and high risk infants, Canada, 2002–12.

Gestational age	INTERGROWTH standard				Canadian reference				INTERGROWTH vs.
category and									Canadian criteria
centile group	Frequency		Composite		Frequency		Composite		Rate ratio	P value
			morbidity and				morbidity and		(95% CI)
			mortality/1000				mortality/1000
	No.	Rate	No.	Rate	No.	Rate	No.	Rate
33–36 weeks	146,669	100.0	8,056	54.9	146,669	100.0	8,056	54.9	-	-
<3rd	2,816	1.92	263	93.4	3,759	2.56	348	92.6	1.01 (0.87–1.18	0.91
3rd to <10th	5,629	3.84	408	72.5	10,191	6.95	698	68.5	1.06 (0.94–1.19	0.35
10th to <50th	40,602	27.7	2,207	54.4	57,393	39.1	3,044	53.0	1.02 (0.97–1.19)	0.37
50th to 90th	72,225	49.2	3,824	52.9	59,100	40.3	3,011	50.9	1.04 (0.99–1.09)	0.10
>90th to<97th	14,894	10.2	745	50.0	10,581	7.21	562	53.1	0.94 (0.85–1.05)	0.27
>97th	10,503	7.16	609	58.0	5,643	3.85	392	69.5	0.83 (0.74–0.94)	0.004
37–43 weeks	2,607,148	100.0	27,193	10.4	2,607,148	100.0	27,193	10.4
<3rd	21,069	0.81	845	40.1	58,799	2.26	1,585	27.0	1.49 (1.37–1.61)	<0.0001
3rd to <10th	65,608	2.52	1,234	18.8	161,619	6.20	2,350	14.5	1.29 (1.21–1.38)	<0.0001
10th to <50th	632,717	24.3	7,370	11.6	1,009,879	38.7	10,304	10.2	1.14 (1.11–1.18)	<0.0001
50th to 90th	1,257,474	48.2	11,489	9.14	1,083,474	41.6	9,755	9.00	1.01 (0.99–1.04)	0.28
>90th to<97th	375,577	14.4	3,431	9.14	201,153	7.72	1,968	9.78	0.93 (0.88–0.99)	0.01
>97th	254,703	9.77	2,824	11.1	92,224	3.54	1,231	13.3	0.83 (0.78–0.89)	<0.0001

Composite neonatal morbidity/mortality included neonatal seizures, assisted ventilation, birth asphyxia, and neonatal mortality.