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. 2017 Mar 3;12(3):e0173429. doi: 10.1371/journal.pone.0173429

Fig 6. Doxorubicin (Doxo) induces an influx of macrophages and neutrophils in conventionally-raised (CONV) mice, but not in germ free (GF) mice.

Fig 6

A. Quantification of the number of macrophages (F4/80+) per crypt unit in CONV and GF jejunal tissue from control mice, 6 hours, 3 days and 5 days after Doxo treatment. B. Quantification of the number of neutrophils (anti-neut+) per crypt unit in CONV and GF jejunal tissue from control mice, 6 hours, 3 days and 5 days after Doxo treatment. n = 3 per time point per group. * = values significantly different from respective control; P<0.05. # = values significantly different between groups (CONV & GF) within a specific time point; P<0.05.