Table 5. Combinatory classification for emetine with existing antimalarials using the CalcuSyn analysis method.
Drug | CI Values at | |||
---|---|---|---|---|
ED50 | ED75 | ED90 | r | |
DHA+Eme (1:10) | 1.803 | 1.805 | 1.808 | 0.899 |
CQ+Eme (4.6:1) | 1.469 | 1.489 | 1.517 | 0.877 |
ATQ+Eme (1:46) | 0.516 | 0.834 | 1.403 | 0.912 |
The combinatory index values are shown for the combination at the ED50, ED75 and ED90 levels of inhibition. The r value for each combination is also reported to indicate the correlation coefficient of the data to the mass action law.