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. 2017 Mar 3;12(3):e0173303. doi: 10.1371/journal.pone.0173303

Table 5. Combinatory classification for emetine with existing antimalarials using the CalcuSyn analysis method.

Drug CI Values at
ED50 ED75 ED90 r
DHA+Eme (1:10) 1.803 1.805 1.808 0.899
CQ+Eme (4.6:1) 1.469 1.489 1.517 0.877
ATQ+Eme (1:46) 0.516 0.834 1.403 0.912

The combinatory index values are shown for the combination at the ED50, ED75 and ED90 levels of inhibition. The r value for each combination is also reported to indicate the correlation coefficient of the data to the mass action law.