Table 1. Characteristics of patients with primary and secondary MN.
| MN | PrimaryMN | Secondary MN | ||
|---|---|---|---|---|
| Variable | N = 108 | N = 85 | N = 23 | p-value |
| Age at diagnosis(years) | 55.2 [40.3; 67.7] | 54.0 [40.5; 65.1] | 55.7 [35.6 ; 75.9] | 0.3542 |
| Sex | 0.8965 | |||
| Female | 41 (38.0) | 32 (37.6) | 9 (39.1) | |
| Male | 67 (62.0) | 53 (62.4) | 14 (60.9) | |
| Proteinuria (g/d) | 6.6 [3.2; 10.8] | 7.1 [3.5; 10.8] | 4.7 [1.9 ; 12.0] | 0.2724 |
| Serumalbumin (g/L) | 20.0 [15.9; 26.0] | 20.0 [16.0; 26.0] | 23.3 [11.9 ;30.0] | 0.8690 |
| Nephrotic syndrome | 0.0092 | |||
| Yes | 83 (76.9) | 70 (82.4) | 13 (56.5) | |
| No | 25 (23.1) | 15 (17.6) | 10 (43.5) | |
| eGFR (mL/min) | 78.8 [57.8; 99.0] | 74.0 [58.0; 99.0] | 81.0 [51.2 ; 98.0] | 0.9284 |
| PLA2RAg | <0.0001 | |||
| Positive | 68 (73.9) | 62 (83.8) | 6 (33.3) | |
| Negative | 24 (26.1) | 12 (16.2) | 12 (66.7) | |
| PLA2R-Ab | <0.0001 | |||
| Positive | 48 (55.2) | 46 (67.6) | 2 (10.5) | |
| Negative | 39 (44.8) | 22 (32.4) | ||
| Follow-up (months) | 30.4[17.7 ; 56.7] | 31.8[18.0; 56.9] | 22.0 [12.6 ; 49.2] | 0.1029 |
| Remission | ||||
| No remission | 32 (317) | 27 (33.8) | 5 (23.8) | |
| Partial remission | 33 (32.7) | 28 (35.0) | 5 (23.8) | |
| Complete remission | 36(35.6) | 25(31.3) | 11 (52.4) |
Frequencies (percentage) or medians (interquartile range) are shown. Quantitative variables were compared by a Student’s t-test or a Wilcoxon rank-sum test, and categorical variables were compared by a Pearson's Chi-square test or Fisher’s exact test.