Table 2.

Verruciform xanthomas of the scrotum

Case	AO (year)	Duration	Race	Location	Morphology	Color	Sizea	Ref.
1	19	20 years	NA	L	Lob, ML	Pinkish	32 mm	[24]
2	19	NA	NA	NA	NA	NA	15 × 11 mm	[36]
3	35	NA	N	NA	Cyst, crateriform	NA	0.8 cm	[18]
4	40		W	R	Ped, v	NA	9 × 5 mm	[28]
5	40	7 years	NA	NA	Ped, flat, g surf, caul	Pink	1 cm	[41]
6	40	20 years	NA	NA	3 nod, pebbly surf	Y–R	7, 9, and 12 mm	[33]
7	44	3 years	NA	NA	Ped, spherical, g surf, caul	Pink	3 cm	[41]
8	49	2–3 years	J	L	Elastic soft, ped, g surfb	R w Y	10 mm	[34]
9	50	Few months	B	L	V, fil p	Pink	4 × 2 mm	[27]
10	50	2 years	B	NA	Sessile plaque	NA	1.2 cm	[32]
11	53	>1 year	NA	NA	Wl, polypoid	NA	0.5 cm	[18]
12	59	4 years	NA	NA	Mult p	Pink	1–1.5 cm	[22]
13	59	3 years	NA	NA	Polyp v nod, pebbly surf	Y–R	6 mm	[33]
14	59	3 week	NA	L	Fil p	R	5 × 4 × 4 mm	[63]
15	63	4 years	J	R	Ped, v, occ bleeding	R-pink	2.5 × 2.5 cm	[30]
16	63	NA	NA	NA	V nodc	Whitish	4 mm	[31]
17	64	3.5 years	NA	NA	polypoid	NA	1.8 cm	[18]
18	66	1 year	J	NA	2 ker pap	Y	4 mm	[25]
19	68	2 years	NA	R	ML nods	E	20 mm	[21]
20	68	12 years	J	R	Ped, v tumor	Pink	10 mm	[42]
21	70	3 years	NA	L	SL ped nods	E	30 mm	[21]
22	71	5 years	J	R	Ped, elastic, soft nod, ML, erosive surf	R	7 × 10 mm	[35]
23	72	2 years	NA	L	Nods	Pink	6 mm	[21]
24	74	1 year	J	L	Well-def	Pinkish	13 mm	[23]
25	75	10 months	J	R	Soft, ped, gran	Y	3 cm	[29]
26	75	1 year			Polyp v nod, pebbly surfd	Y–R	7 mm	[33]
27	78	1 year	J	L	Firm p surround ped node	Y–R	2–5 mm	[25]
28	78	NA	NA		WL, p	Pink	NA	[26]
29	80	3 years	W	L	p	R	8 × 5 mm	CR
30	82	6 months	W	L	Ped, soft, ML	Pinkish	15 mm	[24]
31	83	5 years	NA	NA	Ped, soft, ML	Pink	25 mm	[24]
32–135	e–j				V, WL			[2, 26, 34, 46, 56]

AO age onset, B Black, C case, caul cauliflower-like, CR current report, fil filiform, g granular, J Japanese, L location, m months, ML mulberry-like, mult multiple, NA not available, nod(s) nodule(s), occ occasional, p papules, ped pedunculated, poly polypoid, R red, Ref reference, SL strawberry-like, surf surface, v verrucous, w with, wk weeks, WL wart like, Y yellow, y year(s)

^aSize is reported as given in the case reports. This is measured in either in diameter, length × width, or length × width × height

^bThree red papules about 1 mm in diameter were scattered in the surrounding area of the lesion. The patient noticed a nodule on the nonpsoriatic part of his scrotum while receiving systemic and topical PUVA therapy. The nodule appeared when the cumulative UVA dosage reached 27.6 J/cm²

^cThis patient had four 2–3-mm diameter red papules adjacent to his 7 mm verrucous nodule

^dThe patient also had a pulsating subcutaneous induration covered by lightly purplish skin under his scrotal nodule

^eJoshi and Ovhal [2] documented a case of a single scrotal lesion that was diagnosed as a verruciform xanthoma in their report. There was no other information available on the patient

^fMehra et al. stated that one patient in their study had 2 scrotal lesions appearing at different times in the same year [46]. No other information about the lesions was given

^gFukuda H and Saito R performed a review of the Japanese dermatological literature in 2005 and found 100 scrotal cases that were not cited in this review. 36.3% of the lesions were on the left of the scrotum, 31.4% were on the right of the scrotum, 6.9% were bilateral, and 25.4% did not specify [34]

^hFurue et al. conducted a study using a sample from a scrotal verruciform xanthoma from a 69-year-old man. No other information about the patient was reported [56]

ⁱHelm et al. reported an additional scrotal case with no other information [26]