Fig. 4.
Coversin reduced E-selectin expression. Myocardium was stained with antibody against E-selectin. E-selectin expression was increased in placebo treated animals in the border zone of the AAR and unchanged in the center of the AAR and non-ischemic Cx control region (left panels). Coversin treatment led to significant decrease of E-selectin, expressed by reduced density of staining (middle and right panels). Horizontal line denotes mean [n = 8 (placebo) and n = 7 (coversin)]. Mann–Whitney U test