Fig. 6.

Coversin did not reduce LTB4. a LTB4 was assessed in plasma throughout the study period. LTB4 showed a non-significant trend to lower values during reperfusion in coversin treated animals compared to placebo. LTB4 in myocardial tissue from three different regions at the end of the experiment was not affected by Coversin treatment (filled bars) in comparison to control (open bars) (all p > 0.1). Values presented as mean ± SD. a Linear mixed effect model, b two-way ANOVA with post hoc Bonferroni correction for multiple testing