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High fructose consumption increases adiposity. Beginning at 6–8 wk of age, male mice were fed standard chow diet and water [control (Con); ● and black bars] or 60% fructose diet + 30% fructose water (HFr; ○ and open bars) for 6 wk. A: body weights of HFr and control mice; n = 8–10. B: %body fat and lean mass; n = 7 mice in each group. C–E: fasting serum uric acid (C), triglyceride (D), and free fatty acid (E) levels; n = 7 in each group. ***P < 0.001 by Student's t-test.
