Fig. 1.

Structure of adult and aged mesenteric microvascular networks. A and B: representative examples of the structure of adult (A) and aged (B) mesenteric microvascular networks. C and D: infusion of fluorescent dextran was used to assess vessel perfusion and permeability in adult (C) and aged (D) microvascular networks. E and F: quantification of the total vascular area normalized to tissue area (E) and vascular length normalized to vascular area (F). *Significant difference between adult and aged groups (P < 0.05). Scale bars = 200 µm.