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. 2016 Dec 23;312(2):L288–L296. doi: 10.1152/ajplung.00476.2016

Fig. 4.

Fig. 4.

Comparison of ELF from Leukosorb strips and traditional nasal lavage fluid (NLF) for detection of biomarkers of immune status. The immediate-elution group from the ELF storage condition study was compared with visit 1 (v1) NLF from the same subjects. A: IL-1β levels in ELF vs. NLF. Significantly more IL-1β was detected in the ELF than the NLF. B: IL-6 levels in ELF vs. NLF. C: IL-8 levels in ELF vs. NLF. Significantly more IL-8 was detected in ELF than in NLF. In addition, there was a significant sex difference in the immediate-elution group, in which IL-8 levels were higher in men than in women. D: IP-10 levels in ELF vs. NLF. Significantly more IP-10 was detected in ELF than in NLF. E: neutrophil elastase (NE) levels in ELF vs. NLF. Significantly more NE was detected in ELF than NLF. In addition, there was a significant sex difference in the immediate elution group, in which NE levels were higher in men than in women. F: day-to-day variability in IL-8 NLF. NLF from the 2 days of collection were compared, and there was no variability detected between the 2 days; n = 10; v2 indicates visit 2. Statistical analysis included a paired t-test comparing ELF with NLF. Sex difference was detected using a two-way ANOVA with sex and storage condition as factors with a Dunnett’s post hoc test comparing all groups with the immediate elution group. *P ≤ 0.05, ***P ≤ 0.001.