Table 5.
Significant SNP-SNP interaction odds ratios from pair wise logistic regression with acute coronary syndromea
| Type of interaction | SNP pair | Odds ratio | p value | |
|---|---|---|---|---|
| BUD13–intergenic variants of APOA5-APOA4 genes | rs10488699:G>A | rs633389:C>T | 0.17 | 1.48 × 10−05 |
| rs10488699:G>A | rs1263163:G>A | 0.10 | 9.82 × 10−09 | |
| rs2187126:A>G | rs633389:C>T | 0.04 | 1.95 × 10−07 | |
| rs2187126:A>G | rs1263163:G>A | 0.06 | 5.17 × 10−08 | |
| Intronic variants of BUD13–ZPR1–genes | rs11216126:A>C | rs6589566:A>G | 2.62 | 2.11 × 10−05 |
| rs11216129:C>A | 2.48 | 8.22 × 10−05 | ||
| rs180326:A>G | 0.36 | 5.61 × 10−05 | ||
| rs2075295:T>C | 2.76 | 2.46 × 10−06 | ||
| rs17119975:T>C | 2.66 | 1.71 × 10−05 | ||
| rs1263149:A>G | 0.34 | 1.78 × 10−06 | ||
| rs623908:A>G | 2.39 | 4.17 × 10−05 | ||
| rs2041967:A>G | 2.69 | 4.67 × 10−06 | ||
| ZPR1–intergenic variants of APOA5-APOA4 genes | rs6589566:A>G | rs1263163:G>A | 4.31 | 4.59 × 10−06 |
| Within the intergenic variants of APOA5-APOA4 genes | rs1263163:G>A | rs1263171:G>A | 0.35 | 2.87 × 10−05 |
| rs1263163:G>A | rs2849165:G>A | 0.04 | 2.85 × 10−12 | |
aNo SNP-SNP interaction was significant in case of angina and MI