Table 2.
The three NSP and elastin fibre degradation production
| Variables | CAE (n=30) | CAD (n=30) | Control (n=29) | P | P1 | P2 | P3 |
|---|---|---|---|---|---|---|---|
| HNE, ng/mL | 34.86±10.17 | 26.66±4.24 | 26.22±4.23 | 0.000 | 0.000 | 0.000 | 0.387 |
| CG, pg/mL | 659.82±262.33 | 544.08±132.38 | 507.59±180.17 | 0.031 | 0.027 | 0.016 | 0.184 |
| PR3, ng/mL | 1.30±0.33 | 1.22±0.19 | 1.24±0.20 | 0.376 | 0.574 | 0.927 | 0.628 |
| sElastin, ng/mL | 22.67±11.71 | 13.86±5.46 | 10.13±1.03 | 0.000 | 0.001 | 0.000 | 0.380 |
P values for comparison among groups and comparison between groups using the LSD method: P1, CAE group vs. CAD group; P2, CAE group vs. Control group; P3, CAD group vs. Control group. The significance level was 0.05. CAD - coronary artery disease; CAE - coronary artery ectasia; Control - control group; CG - cathepsin G; HNE - human neutrophil elastase; PR3 - proteinase 3; sElastin - soluble elastin