Figure 1.

a, b. The effect of alpha-lipoic acid, glibenclamide, and both compounds on blood pressure after a single administration

The data represent systolic (a) and diastolic (b) blood pressure, means±S.E.M., after the administration of alpha-lipoic acid (50 mg/kg b.w., intraperitoneal injection)-LA group, or glibenclamide (50 mg/kg b.w., intraperitoneal injection)–G group, or alpha-lipoic acid (50 mg/kg b.w., intraperitoneal injection) plus glibenclamide (50 mg/kg b.w., intraperitoneal injection)-LA+G group, or 1% Tween 80 (0.25 mL, intraperitoneal injection)-control group; *significant LA group vs. control group in each time point: *P<0.05, **P<0.01 (two-way ANOVA, Bonferroni’s multiple comparison test)