Table 13.

Initial and continuous infusion doses of vasodilators^* (2)

	Initial dose	Infusion dose	Precautions
Nitroglycerine	10-20 pg/min	5-200 pg/min	Tolerance and tachyphylaxis on continuous use
Isosorbide dinitrate	1 mg/h	1-10 mg/h
Nitroprusside	0.3 p/kg/min	0.3-10 pg/kg/min	Invasive hemodynamic monitoring is required; marked hypotension may occur; longer infusions may cause thiocyanate toxicity.
Nesiritide	2 pg/kg (bolus)	0.01 pg/kg/min	Hypotension
Ularitide		15 ng/kg/min	Increased sweating, dizziness, nausea and hypotension
Serelaxin		30 pcg/kg/day	Hypotension

^*Modified from ESC 2012 heart failure guidelines (2)