Table 7.

Definitions of worsening heart, renal and liver failure in acute heart failure (53)

Worsening heart failure	Failure to improve or worsening signs and symptoms of HF despite therapy that occurs •after 1-2 days (usually in the first 7 days) of hospitalization and •requires initiation or intensification of parenteral therapy (e.g. inotropes or vasoactive agents) or •implementation of mechanical cardiac or ventilatory support
Worsening renal failure	Increase in serum creatinine >0.3 mg/dL or decrease in estimated glomerular filtration rate >25% after admission
Ischemic hepatopatitis	Decreased blood supply (due to shock or low blood pressure) to liver resulting in liver injury and marked elevation of liver function tests
Congestive hepatopathy	Liver dysfunction due to venous congestion, usually right heart failure