Table 2.
The baseline characteristics and laboratory findings of patients with low, intermediate, and high GRS
| Variable | Low GRS (n=90) | Intermediate GRS (n=104) | High GRS (n=93) | P |
|---|---|---|---|---|
| Age, years | 52±10a,b | 63± 10b,c | 70±10a,c | <0.001 |
| Heart rate, bpm | 70±13a,b | 76±14b | 80±16a | <0.001 |
| Creatinine, mg/dL | 0.8±0.2 | 0.9±0.2 | 0.8±0.2 | 0.166 |
| BUN, mg/dL | 12±3.7 | 11.8±3.7 | 11.8±3.4 | 0.928 |
| Systolic BP, mm Hg | 141±26 | 137±26 | 135±25 | 0.358 |
| Diastolic BP, mm Hg | 90±16 | 87±16 | 86±16 | 0.248 |
| Body mass index, kg/m2 | 25.5±5.5 | 25.3±5.4 | 25.4±5.3 | 0.968 |
| Left ventricle EF, % | 46.7±8.9 | 47.5±10.5 | 49.6±9.6 | 0.127 |
| Female, % (n) | 15.6 (14)a | 26 (27) | 33.3 (31)a | 0.021 |
| Smoking, % (n) | 27.8 (25) | 32.7 (34) | 34.4 (32) | 0.606 |
| GRS | 84.4±19.8a,b | 124.3±8.8b,c | 162.8±18.5a,c | <0.001 |
| TRI | 14.1±5.9a,b | 22.8±8.1b,c | 30.3±10.1a,c | <0.001 |
| SYNTAX score | 9.9±8.3a,b | 12.6±6.9b,c | 17.9±6.7a,c | <0.001 |
| Diabetes mellitus, % (n) | 31.1 (28) | 40.4 (42) | 48.4 (45) | 0.058 |
| Hypertension, % (n) | 52.2 (47) | 44.2 (46) | 39.8 (37) | 0.231 |
| Type of ACS, % (n) | 0.001 | |||
| NSTE-ACS | 80 (72)a,c | 52.9 (55)b,c | 29 (27)a,c | |
| STE-ACS | 20 (18)a,c | 47.1 (49)b,c | 71 (66)a,c | |
| Culprit lesion, % (n) | ||||
| LAD | 37.8 (34) | 49 (51) | 48.4 (45) | 0.223 |
| Cx | 40 (36)a | 23.1 (24) | 17.2 (16)a | 0.001 |
| RCA | 25.6 (23) | 30.8 (32) | 34.4 (32) | 0.425 |
| Glucose, mg/dL | 145±77a | 153±73 | 172±81a | 0.044 |
| LDL, mg/dL | 128.1±33.3 | 123.1±37.7 | 118.4±36.4 | 0.190 |
| HDL, mg/dL | 40.3±12.1 | 43±12.4 | 44±17.5 | 0.199 |
| Triglyceride, mg/dL | 151.4±70.4 | 135.6±54.2 | 133.8±52.1 | 0.086 |
| Hemoglobin, g/dL | 13.7±1.8a | 13.4±2.1 | 12.9±1.8a | 0.028 |
| Neutrophil, 103/mm3 | 8.3±3.9 | 8.2±3.6 | 8.8±4.3 | 0.507 |
| Lymphocyte, 103/mm3 | 4.1±3.6 | 4±3.2 | 3.6±3.2 | 0.557 |
| NLR | 3±2.4 | 2.8±1.8° | 3.7±2.7c | 0.016 |
| hs-TnT, ng/L | 625±1099 | 488±893 | 676±1259 | 0.451 |
P<0.05 between the low and high GRS groups,
P<0.05 between the low and intermediate GRS groups,
P<0.05 between the intermediate and high GRS groups, ACS - acute coronary syndrome; BP - blood pressure; bpm - beats per minute; BUN - blood urea nitrogen; Cx - circumflex; EF - ejection fraction; GRS - Grace risk score; HDL - high-density lipoprotein; Hs-TnT - high-sensitivity troponin-T; LAD - left anterior descending; LDL - low-density lipoprotein; NLR - neutrophil-lymphocyte ratio; NSTE-ACS - non-ST elevated acute coronary syndrome; RCA - right coronary artery; STEMI - ST elevation myocardial infarction; TRI - TIMI risk index
one-way ANOVA and chi-square test