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. 2017 Feb 16;2017:7187232. doi: 10.1155/2017/7187232

Table 2.

Reasons for deviating from the protocol.

Reasons for terminating or tapering morphine earlier than protocolized (N = 43) n

Respiratory depression 14
Sleepiness 11
Too slow awakening after cessation of sedation 9
Nausea 2
Discrepancy between patients' high pain score and behavior according to the nurse 2
Hypotension 1
Delirium suspected to be caused by morphine 1
Refusal of a patient to receive more morphine 1
Decrease of pain immediately after removal of chest tubes 1
Planned extubation directly after pain scoring 1

Reasons for not tapering morphine infusion upon NRS 0 or 1 (N = 7) n

Painful in the previous shift 2
Pain assessments were only within a few hours after surgery 2
Hypertension 2
Low pain scores in rest, but still painful while moving 1

Respiratory depression was defined as respiratory rate of less than 10/min or pCO2 of 7 kPa or more. None of the patients with respiratory depression was reintubated or required naloxone.