Table 3.
Multivariate Cox proportional hazards analysis in 93 LSCC patients. N: number; Ref: reference category; HR: hazard ratio; CI: confidence interval.
| Characteristics | N | P value | HR | 95% CI |
|---|---|---|---|---|
| Age | 93 | 0.979 | 0.999 | 0.953–1.048 |
| Smoking behavior | ||||
| No (Ref) | 18 | — | 1 | — |
| Yes | 75 | 0.288 | 0.636 | 0.276–1.465 |
| Differentiation | ||||
| Well (Ref) | 45 | — | 1 | — |
| Moderated | 35 | 0.256 | 0.656 | 0.318–1.356 |
| Poorly | 13 | 0.24 | 0.512 | 0.167–1.566 |
| Clinical stage | ||||
| Stage I (Ref) | 29 | — | 1 | — |
| Stage II | 19 | 0.783 | 1.196 | 0.336–4.257 |
| Stage III | 12 | 0.053 | 3.735 | 0.982–14.208 |
| Stage IV | 33 | 0.019 | 4.238 | 1.272–14.117 |
| Lymphatic metastasis | ||||
| No (Ref) | 64 | — | 1 | — |
| Yes | 29 | 0.723 | 1.172 | 0.489–2.809 |
| Methylation | ||||
| No (Ref) | 27 | — | 1 | — |
| Yes | 66 | 0.045 | 2.71 | 1.024–7.177 |