Table 2.2.
Univariate analysis of predictors of overall survival (time from definitive surgery)
| Alive |
Dead |
|||||
|---|---|---|---|---|---|---|
| Characteristics | No. | % | No. | % | HR (95% CI) | P-value |
| Total patients | 142 | 86 | 24 | 14 | ||
| Age (continuous) | 1.02 (0.99, 1.05) | 0.2757 | ||||
| Age group | ||||||
| <50 years | 66 | 87 | 10 | 13 | 1 | - |
| 50+ years | 76 | 84 | 14 | 16 | 1.29 (0.55, 3.01) | 0.5620 |
| LVI | ||||||
| No | 87 | 95 | 5 | 5 | 1 | - |
| Yes | 55 | 74 | 19 | 26 | 4.35 (1.61, 11.79) | 0.0039* |
| Subtype | 0.0898 | |||||
| Hormone positive/HER2 negative | 67 | 93 | 5 | 7 | 1 | - |
| HER2 positive | 51 | 88 | 7 | 12 | 1.52 (0.46-4.97) | 0.4927 |
| TNBC | 24 | 67 | 12 | 33 | 4.23 (1.47-12.17) | 0.0076* |
| Post-surgical stage and nodal status | 0.1434 | |||||
| pCR | 33 | 97 | 1 | 3 | 1 | - |
| T+, N negative | 35 | 92 | 3 | 8 | 2.97 (0.31, 28.59) | 0.3470 |
| N+, regardless of T | 74 | 79 | 20 | 21 | 5.89 (0.79, 44.13) | 0.0844 |
| Size (continuous) | 0.98 (0.79-1.22) | 0.8585 | ||||
| Size | ||||||
| 0-5 cm | 110 | 85 | 19 | 15 | 1 | - |
| >5 cm | 32 | 91 | 3 | 9 | 0.65 (0.19-2.18) | 0.4802 |
| Grade | ||||||
| low | 49 | 91 | 5 | 9 | 1 | - |
| High | 89 | 82 | 19 | 18 | 1.96 (0.72, 5.32) | 0.1854 |
Abbreviations: HR, Hazard ratio; CI, confidence interval; LVI: lymphovascular invasion; pCR: pathologic complete response; TNBC: Triple Negative Breast Cancer