Figure 2.

Example of the uniqueness analysis method for the most active electrodes in the target (CA3) region that are specific to one stimulation source in DG. (A) Uniqueness analysis applied to the spike rates (in Hz) of five target (CA3) electrodes for two stimulation sites in DG. (B) Adjacency matrix based on the highest spike rate evoked by each stimulation site shown in panel (A). (C) For panel (B) adjacency matrix, uniqueness index for the i^th target electrode and regional target uniqueness (i.e., the average of the uniqueness measures over all target electrodes). (D) Considering the two highest spike rates evoked by each stimulation source, a new adjacency matrix yields the same regional average in this example. (E) Uniqueness analysis considering the target electrodes with the 3 (E 1.1 and 2.1), 4 (E 1.2 and 2.2), and 5 (E 1.3 and 2.3) highest spike rates evoked by each stimulation source. By considering zeroes (1.1, 1.2, and 1.3) uniqueness reaches an asymptote of zero. By excluding zeroes (2.1, 2.2, and 2.3), uniqueness produces a plateau.